328-73-4, name is 1-Iodo-3,5-bis(trifluoromethyl)benzene, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 328-73-4
General procedure: A mixture of trisallene 3 (0.25 mmol), aryl/hetereoaryl iodides (0.90 mmol), nucleophiles (0.90 mmol), Pd2(dba)3 (2.5 mol percent), TFP (tri-(2-furyl)phosphine) (10 mol percent), and K2CO3 (1.5 mmol) in MeCN (5 mL) was stirred and heated at 80 °C (oil bath temperature) until the starting material was completely consumed as monitored by TLC (see Table 1). The mixture was worked up as mentioned in general procedure A.
The synthetic route of 328-73-4 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Gu?ltekin, Zeynep; Elboray, Elghareeb E.; Aly, Moustafa F.; Abbas-Temirek, Hussien H.; Shepherd, Helena J.; Grigg, Ronald; Tetrahedron; vol. 70; 33; (2014); p. 4934 – 4941;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com