Adding a certain compound to certain chemical reactions, such as: 19099-54-8, name is 1-Iodo-2-isopropylbenzene, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 19099-54-8, Application In Synthesis of 1-Iodo-2-isopropylbenzene
0.3 mmol of sodium carbonate, 0.1 mmol of 1,2-bis(4-methylphenyl)acetylene, 0.005 mmol of palladium acetate, 0.005 mmol of bis(2-diphenylphosphinophenyl)ether, and 0.15 of diboronic acid. 12.5 mmol of mmol, 2-isopropyl iodobenzene and 1 mL of N,N-dimethylformamide were added to a 15 mL reaction tube, and the nitrogen was repeatedly filled 10 times, placed in an oil bath at 120 C, and reacted for 24 hours; The reaction solution was diluted with ethyl acetate at room temperature and washed with water three times.The organic phase is dried over anhydrous Na2SO4.Filtration, concentration and purification by thin layer chromatography gave 28.5 mg of the desired product was obtained in a yield of 63%..The nuclear magnetic and high resolution mass spectra of this compound are characterized as follows:
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Iodo-2-isopropylbenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Huaqiao University; Cheng Guolin; Lv Weiwei; (10 pag.)CN109879899; (2019); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com