Extended knowledge of C8H7IO2

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 82998-57-0.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 82998-57-0, name is 3-Iodo-4-methylbenzoic acid, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C8H7IO2

Thionyl chloride (8. 2ml) was added to a mixture of 3-iodo-4-methylbenzoic acid (18.5g) in chloroform (100ml) and heated at 61C for 16 hours. The solvent was removed under vacuum and excess thionyl chloride removed by azeotroping with toluene (3x30ml). The title compound was formed as a beige solid (19. 5g) and used in subsequent reactions without further purification. NMR H [d6-DMSO] 8.31 (1H, d), 7.87 (1H, dd), 7.46 (1H, d), 2.43 (3H, s).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 82998-57-0.

Reference:
Patent; SMITHKLINE BEECHAM CORPORATION; WO2004/10995; (2004); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com