In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 3930-83-4, name is 2-Iodobenzamide belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Application In Synthesis of 2-Iodobenzamide
General procedure: 2-iodobenzamide 1a (0.261 g, 1 mmol), 1,3-indanedione 2a (0.161 g, 1.1 mmol), cesium carbonate (0.39 g, 1.2 mmol) and copper sulfate pentahydrate (1.25 mg, 5 mumol) in a 100 mL high pressure tube, add 5 mL of water, and then seal the tube.The mixture was rapidly stirred in an oil bath previously heated to 130 C, and it was checked by a TLC sheet whether or not the reaction was completed. After the reaction was completed, the mixture was returned to room temperature, centrifuged, washed with water, and the tube was dried in an oven to obtain a pure product compound (1). Weighing 214 mg, the yield was 82%.
The synthetic route of 3930-83-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Yao Qingfa; (40 pag.)CN109748870; (2019); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com