The important role of

217314-45-9, name is Methyl 3-amino-5-iodobenzoate, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Computed Properties of C8H8INO2

To a0 C solution of aniline from step B (21.7 g, 78.3 mmol) in 3: 1CECl2 : pyridine (75mL) was added methanesulfonyl chloride (6.36mL, 82.2 mmol). The ice bath was removed after 15 minutes and the solution was. stirred overnight at rt. The reaction mixture was extracted several times with INHC1. The organic phase was dried, concentrated, and chromatographed (1: 1 EtOAc: Hex) to afford the desired sulfonamide as a white solid.

The synthetic route of 217314-45-9 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; MERCK & CO., INC.; WO2005/51914; (2005); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com