Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 3058-39-7, name is 4-Iodobenzonitrile, A new synthetic method of this compound is introduced below., Formula: C7H4IN
The compound 4-cyanoiodobenzene 1a (1.0 mmol), DMSO (5 ml), Cs2CO3 (2.0 mmol), and phenol 2a (1.2 mmol) were added to the mixture, and the mixture was stirred at room temperature for 10 minutes. Then placed in an 80 C oil bath, reacted under lightAfter 10 h, after TLC detection reaction, the reaction solution was filtered, extracted and subjected to column chromatography to obtain the target product 4a, yield 79%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; China Three Gorges University; Wang Long; Liu Na; Yang Qingqing; Hu Weimin; (8 pag.)CN109824544; (2019); A;,
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