Application of 42861-71-2, The chemical industry reduces the impact on the environment during synthesis 42861-71-2, name is 3-Iodophenyl acetate, I believe this compound will play a more active role in future production and life.
Example 68; 3 -(2- {6-[(3»S)-3 -(2-Fluorophenoxy)azolan- 1 -yl] -3 -pyridazinyl } – 1 -ethynyl)phenyl acetate; Prepared by Sonagashira coupling reaction of Intermediate 20 with 3-iodophenyl acetate in a mixture of DMSO and triethylamine to give the product as a white solid; IR (PCBr) 2938, 2208, 1762, 1578, 1504, 1371, 1240, 1109, 758 cm”1; 1H NMR (300 MHz, CDCl3) delta 2.26 (br s, IH), 2.30 (s, 3H), 2.48 (br s, IH), 3.76-4.02 (m, 4H), 5.11 (br s, IH), 6.61 (d, J= 9.3 Hz, IH), 6.94-7.10 (m, 4H), 7.29-7.36 (m, 4H), 7.42 (d, J = 9.3 Hz, IH); ESI-MS (m/z) 418.12 (M+H)+.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Iodophenyl acetate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; GLENMARK PHARMACEUTICALS S.A.; WO2008/62276; (2008); A2;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com