Synthetic Route of 645-00-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 645-00-1, name is 1-Iodo-3-nitrobenzene, This compound has unique chemical properties. The synthetic route is as follows.
The chemoselective hydrogenation of nitroarenes was performed in batch reactors. The reactant, internal standard (dodecane), solvent (toluene or THF), and powder catalyst, as well as a magnetic bar, were added into the batch reactor. After the reactor was sealed, air was purged by flushing two times with 10 bar of hydrogen. Then the autoclave was pressurized with H2 to the corresponding pressure. The stirring speed was kept at 800 rpm and the size of the catalyst powder was below 0.02 mm to avoid either external or internal diffusion limitation. Finally, the batch reactor was heated to the target temperature. For the kinetic studies, 50 muL of the mixture was taken out for GC analysis at different reaction times. For the scope studies, 100 muL of the mixture wastaken out for GC analysis. The products were also analyzed byGC-MS.
The chemical industry reduces the impact on the environment during synthesis 1-Iodo-3-nitrobenzene. I believe this compound will play a more active role in future production and life.
Reference:
Article; Liu, Lichen; Concepcion, Patricia; Corma, Avelino; Journal of Catalysis; vol. 340; (2016); p. 1 – 9;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com