Application of 2043-57-4, A common heterocyclic compound, 2043-57-4, name is 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane, molecular formula is C8H4F13I, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A 50 mL three-necked round bottom flask equipped with a stirrer and a dropping funnel was charged with 0.01 mol (0.97 g) of diallyl Amine and 20 mL of anhydrous ether were added to the raw material in an amount of 10% tetrabutylammonium bromide as the catalyst. The reaction was cooled with an ice-water bath. 0.011 mol (5.22 g) of perfluorohexyl ethyl iodide was slowly added dropwise to the reaction system through a dropping funnel in. After dripping, it rises to room temperature. The reaction was stirred for another 6 h. GC tracking reaction end point. After completion of the reaction, the reaction mixture was oxidized with 2% Sodium washing. The organic layer was separated, washed with water, then dried over anhydrous magnesium sulfate, and the solvent was removed by vacuum distillation and excess Fluorohexyl ethyl iodide. 4.16 g of a pale yellow liquid product was obtained in a yield of 93.9%.
The synthetic route of 2043-57-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Guangzhou Liwen Technology Co., Ltd.; Jiangsu Liwen Chemical Co., Ltd.; Jiangxi Liwen Chemical Co., Ltd.; Liang Haibo; Chen Yixin; Xie Wenjian; Wang Jiangbing; Xin Weixian; Chen Xinzi; (21 pag.)CN106866470; (2017); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com