Adding a certain compound to certain chemical reactions, such as: 2401-21-0, name is 1,2-Dichloro-3-iodobenzene, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2401-21-0, Application In Synthesis of 1,2-Dichloro-3-iodobenzene
1.68 g of 17-(m-iodobenzoyloxy)-3-oxo-androst-4-ene-17beta-carboxylic acid and 825 mg of iodobenzene dichloride were gasified with argon in 340 ml of chloroform and exposed for 20 minutes with a mercury high-pressure lamp. The solution was washed with dilute sodium bisulphite solution and water, dried and evaporated in vacuo. Chromatography on silica gel gave 9alpha-chloro-17-(m-iodobenzoyloxy)-3-oxo-androst-4-ene-17beta-carboxylic acid of melting point 236°-237° C.; [alpha]D =-40° (dioxan, c=0.1percent); epsilon220 =34,900.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,2-Dichloro-3-iodobenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Hoffmann-La Roche Inc.; US4252729; (1981); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com