Adding a certain compound to certain chemical reactions, such as: 3930-83-4, name is 2-Iodobenzamide, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3930-83-4, Application In Synthesis of 2-Iodobenzamide
0.5 mmol (123.5 mg) of o-iodobenzamide, 0.05 mmol (8.0 mg) of copper sulfate, 0.1 mmol (19.8 mg) of 1,10-phenanthroline, sodium hydroxide 1 mmol (40 mg), phenylacetylene 0.6 mmol (61.2 mg), tetrabutylammonium bromide 0.1 mmol (32.2 mg), and water 2 mL were added to the reaction vessel. The reaction was carried out in an oil bath at 100 C for 24 hours, cooled to room temperature, the product was extracted with ethyl acetate and concentrated under reduced pressure. The product was purified by column chromatography to give a white solid product in 90% yield.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Iodobenzamide, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Nanyang Normal College; Yu, Lintao; Wang, Huifang; Wang, Zhen; Zhang, Xu; Li, Ting; Yang, Yanbin; Chen, Shaohui; (10 pag.)CN106588767; (2017); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com