Related Products of 3210-08-0,Some common heterocyclic compound, 3210-08-0, name is 4-Iodobutan-1-ol, molecular formula is C4H9IO, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Method A: A solution of [PP(I)P] (215 mg, 0.292 mmol) in THF(10 mL) was added to a stirring suspension of CuI (55.6 mg,0.292 mmol) in THF (5 mL). The cloudy orange reaction mixturewas allowed to stir overnight at 50 C and then filtered throughCelite to obtain an orange filtrate. Removal of the volatiles fromthe filtrate in vacuo afforded analytically pure product as a paleorange solid (88.7 mg, 30% yield).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 4-Iodobutan-1-ol, its application will become more common.
Reference:
Article; Knight, Sadie E.; Bezpalko, Mark W.; Foxman, Bruce M.; Thomas, Christine M.; Inorganica Chimica Acta; vol. 422; (2014); p. 181 – 187;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com