Related Products of 181765-85-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 181765-85-5, name is Methyl 4-chloro-2-iodobenzoate belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Example 45Bmethyl 4-chloro-2-(5-(methoxycarbonyl)-2-nitrophenylamino)benzoate 2470 A solution of Example 3 A (5.35 g, 18.04 mmol), methyl 3-amino-4-nitrobenzoate(3.54 g, 18.04 mmol), CsC03 (5.88 g, 18.04 mmol), palladium(II) acetate (0.202 g, 0.902 mmol) and 1 , 1 ‘-bis(diphenylphosphino)ferrocene ( 1.0 g, 1.804 mmol) in toluene was heated at 95C for 16 hours. The reaction mixture was brought to 80C; filtered through a plug of silica gel and washed with ethyl acetate. The solvent was removed and residue 2475 was purified over silica gel. The material was collected and washed with minimumamount of hot ethanol to yield the title compound. MS ESI(+) m/z 365 [M+H]+.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 4-chloro-2-iodobenzoate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING(SHANGHAI) COMPANY, LTD.; VAN CAMP, Jennifer; PATEL, Jyoti, R.; SWANN, Steven; WO2012/45194; (2012); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com