Reference of 2401-21-0, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2401-21-0, name is 1,2-Dichloro-3-iodobenzene, This compound has unique chemical properties. The synthetic route is as follows.
EXAMPLE 39 Benzyl 3-p-acetamidophenylsulphinyl-3-chloro-7-oxo-1-azabicyclo[3.2.0]heptane-2alpha-carboxylate STR81 A solution of benzyl 3-p-acetamidophenylthio-7-oxo-1-azabicyclo[3.2.0]heptane-2alpha-carboxylate (92) (0.150 g) in chloroform (10 ml) was stirred under argon and treated successively with water (0.007 g), pyridine (0.102 g) and iodobenzene dichloride (0.251 g). After a period of 1 hour at room temperature, the solution was concentrated and then chromatographed on a column of silica gel 60 (<230 mesh) eluding with ethyl acetate. This gave benzyl 3-p-acetamidophenylsulphinyl-3-chloro-7-oxo-1-azabicyclo[3.2.0]heptane-2alpha-carboxylate (64) (0.120 g) as a colourless foam; numax (CHCl3) 3460, 3340, 3000, 1785, 1745, 1700, 1590 and 1510 cm-1; tau(CDCl3) 1.52 (1H, brs, NH), 2.2-2.8 (9H, m, phenyls, 4.74 (2H, s, benzyl CH2), 4.96 (1H, s, C2-H), 5.6-5.9 (1H, m, C5-H), 6.62 (1H, dd J 16 and 5 Hz, C6-H), 6.93 (1H, dd J 16 and 21/2 Hz, C6-H), 7.16 (1H, dd J 15 and 8 Hz, C4-H), 7.86 (3H, s, COCH3) and 8.22 (1H, d J 15 Hz, C4-H).
The chemical industry reduces the impact on the environment during synthesis 1,2-Dichloro-3-iodobenzene. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Beecham Group Limited; US4223038; (1980); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com