627-31-6, name is 1,3-Diiodopropane(stabilized with Copper chip), belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 627-31-6
1,3-iodopropane (27.5g, 93mmol) and 3-methyl-3-hydroxymethyl-oxetane (3.1g, 31mmol), sodium hydroxide (20g, 500mmol) in water and hexane stir in two-phase system, with tetrabutylammonium bromide as phase transfer catalyst, the reaction for 0.5 hours under reflux.After completion of the reaction by extraction, purified by distillation under reduced pressure to give a colorless liquid.Yield: 62%.
The synthetic route of 627-31-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Suzhou Institute of Nano Rui Medical Technology Co., Ltd.; Zhao, Peng; Wu, Liangliang; Liu, Jing; Lin, Chao; Wenxue, Jun; (19 pag.)CN105523946; (2016); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com