Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 41252-98-6, name is 1-Iodo-2-methyl-3-nitrobenzene, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C7H6INO2
4.1.11. 2,20-Dimethyl-3,30-dinitro-1,10-biphenyl (27)4.1.11.1. Activation of copper powder:.34 Copper powder (2.00 g)was stirred with 2% iodine (w/w wrt copper) in acetone (100 mL)for 10 min. The powder was filtered and stirred to form a slurrywith 1:1 solution of concentrated hydrochloric acid in acetone(200 mL). The copper iodide dissolved, and the copper powderremaining was removed by filtration and washed with acetone(200 mL). The activated copper was dried in a vacuum desiccatorand used immediately.2-Methyl-3-nitro-iodobenzene (26) (1.00 g, 3.80 mmol) andactivated copper (1.21 g, 19.0 mmol) were added to dry N,Ndimethylformamide(8 mL), and the mixture was heated to 190 Cfor 24 h. The mixture was diluted with dichloromethane (100 mL),washed with 4% aqueous ammonia (5100 mL), water (450 mL),and brine (350 mL), dried (Na2SO4), and the solvents removedunder reduced pressure to yield a dark crude oil. Column chromatographyof the residue using ethyl acetate/petroleum ether(1:10) gave the product as a yellow solid (0.27 g, 53%); mp120e121 C; nmax (film)/cm1 3086, 1604, 1524, 1458, 1350, 1279,1219, 1106, 995, 859, 807, 736, 718, 674; 1H NMR (400 MHz, CDCl3):d 2.13 (6H, s, 2 CH3), 7.29 (2H, dd, J7.6, 1.4 Hz, 2 CH arom., biphenyl-5,50), 7.36 (2H, ddd, J8.0, 7.6, 0.5 Hz, 2 CH arom., biphenyl-6,60), 7.83 (2H, dd, J8.0, 1.4 Hz, 2 CH arom., biphenyl-4,40); 13CNMR (100 MHz, CDCl3): d 15.4 (2 CH3, 2 ArCH3), 123.1 (2 CHarom., biphenyl-4,40),125.7 (2 CH arom., biphenyl-5,50),129.8 (2 Cquat., arom., biphenyl-2,20), 132.6 (2 CH arom., biphenyl-6,60), 141.3(2 C quat., arom., biphenyl-1,10), 149.9 (2 C quat., arom., biphenyl-3,30); m/z (EI) 272.0793; C14H12N2O4 (M) requires 272.0797.
According to the analysis of related databases, 41252-98-6, the application of this compound in the production field has become more and more popular.
Reference:
Article; Farah, Mohamed M.; Page, Philip C. Bulman; Buckley, Benjamin R.; Blacker, A. John; Elsegood, Mark R.J.; Tetrahedron; vol. 69; 2; (2013); p. 758 – 769;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com