Application of 27913-58-2, The chemical industry reduces the impact on the environment during synthesis 27913-58-2, name is 4-(4-Iodophenyl)butanoic acid, I believe this compound will play a more active role in future production and life.
Figure 1 shows possible building-block reagents, starting from which the compounds of the inventions may be synthesised. The carboxylic acid of compound 428 (obtainable from SIGMA, catalogue number 15634) was activated with one equivalent of EDC and 1.2 equivalents of NHS in DMSO for 4h at 30 0C prior to addition of ten equivalents of 7-aminoheptanoic acid and triethylamine. The reaction was stirred overnight at 30 C, to EPO
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-(4-Iodophenyl)butanoic acid, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; PHILOCHEM AG; WO2008/53360; (2008); A2;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com