Electric Literature of 74-88-4, The chemical industry reduces the impact on the environment during synthesis 74-88-4, name is Iodomethane, I believe this compound will play a more active role in future production and life.
In 10 ml of N,N-dimethylformamide was dissolved 1.8 g (10.6 mmol) of 2-chloro-6-methylbenzoic acid, and then, 1.49 g (10.8 mmol) of potassium carbonate and 2.7 ml of methyl iodide were added to the solution, and the mixture was stirred at room temperature for 3 hours. After completion of the reaction, water was added to the reaction mixture and the mixture was extracted with diethyl ether. The organic layer was successively washed with water and a saturated aqueous sodium chloride solution, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. The residue was applied to silica gel column chromatography (eluent: hexane/ethyl acetate=9/1(volume ratio)) to obtain 1.69 g of the title compound as pale yellowish liquid. CI-MS (m/z); 171 (M++1).1H-NMR (delta, CDCl3); 2.32 (s, 3H), 3.95 (s, 3H), 7.10 (t, J=4.3Hz, 1H), 7.22-7.23 (m, 2H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Iodomethane, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Ube Industries, Ltd.; EP1408033; (2004); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com