Introduction of a new synthetic route about 51560-21-5

The chemical industry reduces the impact on the environment during synthesis 1,4-Diiodo-2,5-dimethoxybenzene. I believe this compound will play a more active role in future production and life.

Electric Literature of 51560-21-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene, This compound has unique chemical properties. The synthetic route is as follows.

To a solution of PdCl2(PPh3)2 (28mg, 0.04mmol), CuI (15.2mg, 0.08mmol), and 2,5-diidodimethoxybenzene (0.78g, 2mmol) in toluene (100ml), was added trimethylsilyacetylene (0.68ml, 4.8mmol) under nitrogen. Triethylamine (0.56ml, 8mmol) was later added dropwise and the reaction mixture was stirred for 24 hours at room temperature. On completion of the reaction (TLC), the solvent was evaporated and the resulting solid residue taken up with dichloromethane. The solution was filtered, concentrated and recrystallized from methanol to give a white-yellowish paste which solidified on standing (0.59g, 90%).

The chemical industry reduces the impact on the environment during synthesis 1,4-Diiodo-2,5-dimethoxybenzene. I believe this compound will play a more active role in future production and life.

Reference:
Article; Tsakama, Madalitso; Shang, Yuting; He, Yonghuang; Fan, Bei; Wang, Fengzhong; Chen, Weihua; Dai, Xiaofeng; Tetrahedron Letters; vol. 57; 16; (2016); p. 1739 – 1742;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com