Application of 766-99-4, The chemical industry reduces the impact on the environment during synthesis 766-99-4, name is 1-Ethynyl-4-iodobenzene, I believe this compound will play a more active role in future production and life.
To a suspended solution of ZnBr2 (1.10 mmol, 0.176 g) and (4-iodophenyl)ethyne (15.3 mmol, 3.50 g) in THF (40 mL) was added tributyl(methoxy)stannane (18.4 mmol, 5.91 g). The mixture was stirred for 3 h at room temperature, and then quenched by NH4F(aq) (10%, 50 mL). The obtained white precipitate was filtered off, and the filtrate was extracted with Et2O (3 x 10 mL) and dried over MgSO4. The volatiles were removed under reduced pressure to give a pure product (100% purity (A small portion was analyzed by 1H NMR using 1,1,2,2-tetrachloroethane as an internal standard to determine the purity)).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Ethynyl-4-iodobenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Suzuki, Itaru; Esumi, Naoto; Yasuda, Makoto; Baba, Akio; Chemistry Letters; vol. 44; 1; (2015); p. 38 – 40;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com