Application of 7681-82-5,Some common heterocyclic compound, 7681-82-5, name is Sodium iodide, molecular formula is INa, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
To a round-bottomed flask were added dichloride(pentamethylcyclopentadienyl)iridium(III) dimer (0.1 mmol, 79.5 mg) and sodium iodide (1 mmol, 150 mg). The round-bottomed flask was equipped with a reflux condenser and capped with a rubber septum. An ultrapure argon flow was passed through the system for 30 min. Then, anhydrous acetone (10 mL) was added using syringe and needle, the ultrapure argon flow was reduced, and the reaction mixture was refluxed under stirring for 3 h. Afterwards, the solvent was evaporated under reduced pressure to give a solid which was dissolved in CH2Cl2 (20 mL), washed with distilled water (3 x 10 mL), and dried over Na2SO4. After filtration, the solvent was evaporated under reduced pressure, affording the desired catalyst. Yield: 107 mg (92%); reddish solid; Rf = 0.41 (eluent: dichloromethane); 1H NMR (300 MHz, CDCl3): delta 1.76 (s, 30H); 13C NMR (75 MHz, CDCl3): delta 88.8, 10.7; IR (KBr, cm-1) 3442.9, 2918.3, 1629.9; HRMS (ESI): m/z [M – I]+ calcd for C20H30I3Ir2: 1036.8740; found: 1036.8713
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Sodium iodide, its application will become more common.
Reference:
Article; Correa, Bianca K.; Silva, Tamiris R.C.; Raminelli, Cristiano; Tetrahedron Letters; vol. 59; 39; (2018); p. 3583 – 3585;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com