Some common heterocyclic compound, 63262-06-6, name is 1,4-Dibromo-2,5-diiodobenzene, molecular formula is C6H2Br2I2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Computed Properties of C6H2Br2I2
Under the protection of nitrogen, 4.85 g of compound II, 2.50 g of trimethylsilylacetylene, 50 ml of triethylamine, 100 mg of cuprous iodide and 150 mg of dichlorobis(triphenylphosphine)palladium were added.Block the reaction system, stir at room temperature overnight, gas phase detectionReaction process, after the reaction is over,The triethylamine was distilled off under reduced pressure, and the column was eluted with a solvent of n-hexane to afford a crude product.White solid 3.2 g, yield 80%.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 63262-06-6, its application will become more common.
Reference:
Patent; Henan Academy Of Sciences Chemical Institute Co., Ltd.; Zhou Yang; Zhao Yongde; Dai Bencai; Liu Changchun; Wang Lantian; Zhang Yuli; Chai Cuncai; Chen Jieying; (11 pag.)CN108558948; (2018); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com