Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 5460-32-2, name is 4-Iodo-1,2-dimethoxybenzene, A new synthetic method of this compound is introduced below., Computed Properties of C8H9IO2
General procedure: A mixture of aryl halide (1 mmol), phenylboronic acid(1.2 mmol), K2CO3 (2 mmol), Fe3O4-AuSF-SBA-15 nanocatalyst(50 mg or 0.64 mmol% of Au) and 5 mL of C2H5OH/H2O (1:1) wereadded to a 25 mL round-bottom flask and stirred at 80 C forappropriate times. After completion the reaction (controlled byTLC), the mixture was cooled and the catalyst was recovered by amagnet and washed three times with ethyl acetate and ethanol.The combined organic layer was dried over MgSO4. Then the solventwas evaporated and the residue was purified by column chromatographyand characterized by its 1H NMR, 13C NMR andmelting point.
The synthetic route of 5460-32-2 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Khodaei, Mohammad Mehdi; Dehghan, Mahsa; Polyhedron; vol. 162; (2019); p. 219 – 231;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com