Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 620-05-3, name is (Iodomethyl)benzene, This compound has unique chemical properties. The synthetic route is as follows., name: (Iodomethyl)benzene
General procedure: A mixture of p-tert-butylcalix[4]arene (1 mmol), potassium carbonate (4 mmol), potassium iodide (20 mol%) in acetonitrile (30 mL) was refluxed at 85 C temperature for 30 min. The reaction mixture was cooled to room temperature and alkyl halide (2.1 mmol) was added to it followed by refluxing (4 mmol for 2m, 2p). The progress of the reaction was monitored byTLC (ethyl acetate/hexane 3:7). After completion, the reaction was cooled to room temperature and the contents were filtered. Solvent was evaporated on a rotary evaporator. The residue obtained was dissolved in chloroform and extracted with water.Chloroform layer was washed with NaCl (brine) and dried over sodium sulfate. Chloroform was evaporated under reduced pressure by using rotary evaporator and the precipitate obtained was recrystallized (chloroform/methanol, 3:7) to afford pure calixarene derivatives.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 620-05-3.
Reference:
Article; Arora, Lakhbeer Singh; Chawla, Har Mohindra; Shahid, Mohammad; Pant, Nalin; Organic Preparations and Procedures International; vol. 49; 3; (2017); p. 228 – 235;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com