Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 626-01-7, name is 3-Iodoaniline, A new synthetic method of this compound is introduced below., Formula: C6H6IN
General procedure: A mixture of substituted aniline (2 mmol), ethyl acetoacetate (1 mmol),RuCl3.3H2O (15 mol%), and ethanol (5 mL) were stirred in a 10 mLround bottom flask at room temperature. After 20 minutes substitutedbenzaldehyde (2 mmol) was added and the reaction mixture was stirredfor the time indicated in Table 3, while being followed by TLC. Aftercompletion of the reaction, the thick precipitate was filtered off andwashed with ethanol (3 × 5 mL) to give the pure product 4.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Mohammadi, Sedigheh; Abbasi, Mohsen; Journal of Chemical Research; vol. 39; 2; (2015); p. 123 – 126;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com