These common heterocyclic compound, 7212-28-4, name is 2-Iodo-N-phenylacetamide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. COA of Formula: C8H8INO
General procedure: 0.4 g (1.61 mmol) of 10, 1.93 mmol of 3a-j and 0.55 g (4.01 mmol) of K2CO3 were combined and refluxed in 20 ml acetone for 2 h. Then the solvent was reduced under reduced pressure. The crude product was washed with water, filtered and dried, followed by recrystallization from petroleum ether and ethyl acetate.
The synthetic route of 2-Iodo-N-phenylacetamide has been constantly updated, and we look forward to future research findings.
Reference:
Article; Liu, Wukun; Hua, Jie; Zhou, Jinpei; Zhang, Huibin; Zhu, Haiyang; Cheng, Yanhua; Gust, Ronald; Bioorganic and Medicinal Chemistry Letters; vol. 22; 15; (2012); p. 5008 – 5012;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com