Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 13101-40-1, name is 1-Bromo-3-chloro-5-iodobenzene, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C6H3BrClI
Weigh 1-bromo-3-chloro-5-iodobenzene and raw material A, dissolve it with toluene, and add Pd2(dba)3, tri-tert-butylphosphine and sodium t-butoxide; The mixed solution of the above reactants is reacted at a reaction temperature of 95 to 110 C under an inert atmosphere for 10 to 24 hours. Cooling and filtering the reaction solution, and the filtrate is steamed and passed through a silica gel column to obtain an intermediate M; The molar ratio of the starting material A to 1-bromo-3-chloro-5-iodobenzene is 1: (1.0-1.5), and the molar ratio of the Pd2(dba)3 to the raw material A is (0.005-0.01): 1 ,The molar ratio of the tri-tert-butylphosphine to the starting material A is (0.005-0.01): 1,The molar ratio of the sodium tert-butoxide to the raw material A is (1-3): 1, The toluene is used in an amount of from 100 to 150 ml of toluene per 0.01 mol of 1-bromo-3-chloro-5-iodobenzene
According to the analysis of related databases, 13101-40-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Jiangsu March Optoelectric Technology Co., Ltd.; Zhao Sijie; Wang Fang; Xie Dandan; Wu Xiuqin; Zhang Zhaochao; (45 pag.)CN109912431; (2019); A;,
Iodide – Wikipedia,
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