Electric Literature of 173043-61-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 173043-61-3, name is Methyl 2-iodo-4,5-dimethoxybenzoate belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: To a solution of ester (10 mmol) in DMF was added indole (10 mmol), CuI (10 mol %) and K2CO3 (30 mmol). The resultant mixture was stirred at 120 oC for 2 h. After completion, the reaction mixture was filtered through celite. The filtrate was extracted with EtOAc, washed with water, brine, and dried over Na2SO4. The solution was concentrated under reduced pressure, and purified by column chromatographed over silica gel to give the desired 2-indolyl ester.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 2-iodo-4,5-dimethoxybenzoate, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Liu, Min; Liu, Yu-Wen; Xu, Hui; Dai, Hui-Xiong; Tetrahedron Letters; vol. 60; 39; (2019);,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com