Some common heterocyclic compound, 1252046-13-1, name is 2-Bromo-5-iodobenzonitrile, molecular formula is C7H3BrIN, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. SDS of cas: 1252046-13-1
Under nitrogen condition, the compound B was dissolved in dioxane, and the compound A (0.9 equivalent) was added. Potassium phosphate (4.0 equivalent) was added, and Cut (0.2 equivalent) and 1,2-diaminocyclohexane (0.2 equivalent) were added. The mixture was refluxed and stirred for 12 hrs, and then the reaction was finished. The resultant was extracted using an organic solvent, and the organic solvent was removed. The resultant was columned and reprecipitated such that the compound C was obtained.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1252046-13-1, its application will become more common.