Electric Literature of 689260-53-5, The chemical industry reduces the impact on the environment during synthesis 689260-53-5, name is 2-Bromo-5-iodo-1,3-dimethylbenzene, I believe this compound will play a more active role in future production and life.
A mixture of 2-bromo-5-iodo-1 ,3-dimethylbenzene (500 mg), 1 ,2,4-triazole (340 mg), potassium carbonate (770 mg), and copper(l) iodide (232 mg) in N-methyl-2- pyrrolidinone is stirred at 130 C over night. More potassium carbonate (770 mg) and copper(l) iodide (232 mg) are added and the mixture is heated to 150 C for 4 h. After cooling to room temperature the mixture is diluted with tetrahydrofuran and filtered. The filtrate is concentrated in vacuo and purified by HPLC on reversed phase to give the title compound. LC (method 7): tR = 0.99 min; Mass spectrum (EST): m/z = 252, 254 [M+H]+.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Bromo-5-iodo-1,3-dimethylbenzene, other downstream synthetic routes, hurry up and to see.