Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6940-76-7, name is 1-Chloro-3-iodopropane, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C3H6ClI
A reaction flask was charged with 6,7-difluoro-4H-benzo [1.4]oxazin-3-one (1.5 g, 8.1 mmol), 1-chioro-3-iodopro-pane (1.44 g, 8.1 mmol), and Cs2CO3 (4.0 g, 12.2 mmol) in MeCN (10 mE) and stirred at rt for 40 h. The reactionmixture was concentrated, water added, and the product extracted into EtOAc. The combined organic phases weredried over Na2SO4, filtered, and concentrated. The productwas purified by flash column chromatography (Si02 n-heptane/EtOAc 2:1) to give the title compound (1.88 g, 89%).?H NMR (CDC13) oe 6.99 (dd, J=8.0 Hz, J=5.6 Hz, 1H), 6.79-6.72 (m, 2H), 4.59 (s, 2H), 4.08 (t, J=7.2 Hz, 2H), 3.62(t, J=6.0 Hz, 2H) 2.18-2.10 (m, 2H); ?3C NMR (CDC13) oe163.9, 159.1 (d, J=244.1 Hz), 146.4 (d, J=11.9 Hz), 124.9 (d,J=3.0 Hz), 115.4 (d, J=9.6 Hz), 109.5 (d, J=22.7 Hz), 105.4 (d, J=26.2 Hz), 67.7, 42.4, 39.2, 30.1.
According to the analysis of related databases, 6940-76-7, the application of this compound in the production field has become more and more popular.