Related Products of 7681-82-5, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 7681-82-5 as follows.
General procedure: Nal (2.15 eq.) is added at room temperature to a suspension of PtCI2(1-R-1 ,5-COD)] (1.00 eq.; synthesized as described in Example 1 ) in acetone. The color of the reaction mixture initially turns yellow and the mixture is stirred for three hours. Afterwards the acetone is removed under reduced pressure and the resulting residue is dissolved in a mixture of dichloromethane and water (1 :1 ). The phases are separated and the organic phase is washed twice with water, dried over sodium sulfate and filtered. After removal of the solvent under reduced pressure, the desired Ptl2(1-R-1 ,5-COD) complex can be obtained as a bright yellow to orange solid or wax.50.0 mg (1 .00 eq., 0.128 mmol) [PtCI2(Me-COD)] and 43.2 mg (2.15 eq., 0.258 mmol) Nal in 3 mL acetone were stirred together for three hours. 71.1 mg (0.126 mmol, 97%) of the desired product could be obtained as yellow solid. – Decomposition temperature: >170 C. – 1H-NMR (400 MHz, CDCI3): delta (ppm) = 1.70- 1.90 (m, 1 H, CH2), 1.90-2.20 (m, 3 H, CH2), 2.08 (s d,2JPtH= 20.7 Hz, 3 H, CH3), 2.20- 2.40 (m, 2 H, CH2), 2.50-2.61 (m, 1 H, CH2), 2.61-2.80 (m, 1 H, CH2), 5.56-6.02 (m, 3 H, CH). -13C-NMR (100 MHz, CDCI3): delta (ppm) = 29.8 (-, CH2), 31 .9 (-, CH2), 32.3 (+, CH3), 32.5 (-, CH2), 36.2 (-, CH2), 99.5 (+, CH), 99.7 (+, CH), 101.1 (+, CH), 128.9 (Cquart). – 195Pt-NMR (129 MHz, CDCl3): delta (ppm) = -4240 (s). – IR (ATR) [cm-1]: v-1= 3000 (vw), 2940 (vw), 2874 (vw), 2825 (vw), 2108 (vw), 1718 (vw), 151 1 (vw), 1492 (vw), 1477 (vw), 1423 (w), 1368 (vw), 1347 (vw), 1335 (vw), 1312 (w), 1237 (vw), 1210 (vw), 1 191 (vw), 1 169 (vw), 1 142 (vw), 1095 (w), 1061 (vw), 1036 (vw), 1022 (vw), 1006 (w), 967 (vw), 939 (vw), 895 (vw), 874 (w), 853 (vw). – MS (70 eV, El), m/z (%): 574/572/571/570 (10/45/60/50) [M+], 445/444/443/442/441 (25/30/36/1 1/15) [M+- l], 316/315/314/313/312/31 1/310 (1 1 Pi 8/12/18/12/17/12) (13/23/76/84/86/55/60/36/38/28/13) [M+-2 I], 122 (52) [C9H14+], 107 (39) [CeHu*], 94 (41 ), 68 (100). – HRMS (Ptl2C9H14): calc. 570.8833; found 570.8831. – EA (Ptl2C9H14): calc. C 18.93, H 2.47; found C 19.70, H 2.58.
According to the analysis of related databases, 7681-82-5, the application of this compound in the production field has become more and more popular.