Related Products of 2043-57-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2043-57-4, name is 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
The starting 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl iodide (12.69 g, 26.8 mmol) was dissolved in the mixture of pentane and diethyl ether (90 and 60 mL). The solution was stirred and cooled to -78 C before the solution of 1.6 M tert-butyllithium in hexane (18.54 mL, 29.7 mmol) was added. The mixture was stirred for 15 min and freshly distilled (2-chloroethyl)trichlorosilane (1.5 g, 7.58 mmol) slowly added with stirring. The reaction mixture was stirred for 2 h at -78 C and 1 h at 0 C then it was poured on ice (ca 10 g) and stirred for further 15 min. The resulting biphasic mixture was filtered through silica gel. The layers were separated and aqueous phase was extracted with diethyl ether (3×50 mL). The combined organic phases were dried (MgSO4) and evaporated to afford the product as a yellow oil. The yield was 8.1 g (7.15 mmol, 94%). 1H NMR: delta (ppm) 1.00 (m, 6H, CH2CH2CF2); 1.40 (t, 3JHH=7.7Hz, 2H, CH2CH2Cl); 2.11 (m, 6H, CH2CF2); 3.72 (t, 3JHH=7.7Hz, 2H, CH2Cl). 13C{1H} NMR: delta (ppm) 1.65 (s, CH2CH2CF2); 16.88 (s, CH2CH2Cl); 25.46 (t, 2JCF=24.0Hz, CH2CF2); 40.68 (s, CH2Cl); 106-122 (m, CF3, CF2). 19F NMR: delta (ppm) -127.05 (m, 2F, CF2); -124.09 (bs, 2F, CF2); -123.69 (bs, 2F, CF2); -122.70 (bs, 2F, CF2); -116.94 (m, 2F, CF2); -81.78 (t, 3JFF=11.1Hz, 3F, CF3). 29Si{1H} NMR: delta (ppm) 6.36 (s, 1Si).
The synthetic route of 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane has been constantly updated, and we look forward to future research findings.