Application of 77317-55-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 77317-55-6, name is Methyl 2-amino-5-iodobenzoate, This compound has unique chemical properties. The synthetic route is as follows.
b) (2-Amino-5-iodo-phenyl)-methanol; Intermediate 17a (14.00 g) was dissolved in dry THF (50 ml_) and 1M diisobutylaluminium hydride in THF (165 ml_) was added dropwise to this solution at -30C. The solution was then stirred at -150C for 1 h. To this mixture MeOH (50 mL) was added portionwise maintaining the temperature of the solution below -5C. The resulting mixture was then at -15C for 18 h. The formed solid was filtered off and washed with MeOH. The organic phase was dried and the solvent was evaporated in vacuo. The residue was purified by flash chromatography (silica gel, 1-5% methanol in dichloromethane) to give the title compound (9.70 g); ESMS m/z 249.9 [M+H]+.
The chemical industry reduces the impact on the environment during synthesis Methyl 2-amino-5-iodobenzoate. I believe this compound will play a more active role in future production and life.