Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 153898-63-6, name is 2-Iodo-5-methoxyaniline, A new synthetic method of this compound is introduced below., Recommanded Product: 153898-63-6
To a solution of 2-iodo-5-methoxy-phenylamine 76a (4.05 g, 16.3 mmole) in [10] ml anhydrous CH2CI2 was added TFAA (4.1 g, 19.5 mmole). The mixture was stirred at [36C] overnight, TLC indicated some starting material remained. Additional TFAA (4.1 g, 19.5 mmole) was added and stirred at [38C] for another 24 hours. The mixture was concentrated under rot vap and purified by column chromatography (eluting with 5-10 % EtOAc in hexanes) to give 4. [6 G] product (81% yield). 1H NMR (300 MHz, [CDCI3) B 7.] 92 [(1 H, D, J= 2.] 8 Hz), 7.66 [(1 H, D, J=] 8.9 Hz), 6.59 (1 H, dd, [J=] 2.8, 8.9 Hz), 3.82 (3H, s).
The synthetic route of 153898-63-6 has been constantly updated, and we look forward to future research findings.