Some common heterocyclic compound, 7425-53-8, name is Ethyl 4-iodobutanoate, molecular formula is C6H11IO2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Recommanded Product: 7425-53-8
Example 2 1-methyl-3-(carboethoxypropyl)-7-(pivaloyloxymethyl)xanthine A mixture of 1-methyl-7-(pivaloyloxymethyl)xanthine (350mg, 1.25 mmes) sodium carbonate (265mg, 2.50 mmoles) and ethyl 4-iodobutyrate (384 mul, 2.50 mmole) in 5.8ml dry DMF was stirred under nitrogen at room temperature for 18 hours. Water was added and the reaction mixture extracted with chloroform. After drying, the extracts were stripped to leave a yellow oil which goes to chromatographed on four thick silica gel plates with 10% EtOH/CHCl3. The band was scraped off and eluted with 100ml of 25% EtOH/CHCl3 to yield 609mg of the desired product as an oil.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 7425-53-8, its application will become more common.