Synthetic Route of 2401-21-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2401-21-0, name is 1,2-Dichloro-3-iodobenzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
I. 17alpha-Chloro-17beta-Methylsulfinyl-11beta-Hydroxy-1,4-Androstadiene-3-One In a manner similar to that described in Example 2A, react 0.475 gm. 17alpha-methylthio-11beta-hydroxy-1,4-androstadiene-3-one, 12 ml. of pyridine, 3 ml. of water and 1.17 gm. of iodobenzene dichloride. Purify the residue by utilizing thin layer silica gel chromatography, developing with acetone/ethyl acetate/chloroform (6:47:47), and eluding with ethyl acetate. Crystallize from acetone/hexane to obtain the title compound; m.p. 230°-233° C. (decomp.); nmr (dmso-d6) delta 1.40 (C10 and C13 –CH3, s), 2.47 (SCH3, s), 4.28 (11alpha-H, mult.), 5.94 (C4 –H, d), 6.16 (C2 –H, dd), 7.29 (C1 –H, d).
The synthetic route of 1,2-Dichloro-3-iodobenzene has been constantly updated, and we look forward to future research findings.