Electric Literature of 31599-61-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 31599-61-8, name is 4-Iodo-1,2-dimethylbenzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: Pd cNPs/CFe3O4(20 mg, 0.73 mol%), aryl halide (0.5 mmol),phenylboronic acid (0.6 mmol), K2CO3(1.5 mmol), and EtOH (3 mL)were taken in a schlenk tube with a teflon stopcock, sealed andheated at 70C for a given time with constant stirring. For chloroderivatives, the reaction was performed using TBAB as additive(0.5 mmol), DMF (3 mL), at 110C and catalyst 40 mg (1.5 mol%).After the completion of reaction, the catalyst was separated by anexternal magnet and reaction mixture was washed with water toremove excess of boronic acids and further the mixture was sepa-rated by ethyl acetate. The solvent was evaporated and the residuewasresiduewas subjected to GC analysis (retention time of halobenzene wasused as the internal standard) followed by column chromatographyfor further purification. The purified compounds were character-ized by1H and13C NMR spectroscopy using CDCl3as solvent andTMS as internal standard. The spectral details and spectra are givenin supporting information section (Figs. S5-S24).
The synthetic route of 4-Iodo-1,2-dimethylbenzene has been constantly updated, and we look forward to future research findings.