Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6213-88-3, name is (E)-Methyl 3-iodoacrylate, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 6213-88-3
Bis (benzonitrile) palladium(II) chloride (0.238 g, 0.62 mmol), t-butyl acetylene (1.31 g, 15.94 mmol) and copper (I) iodide (0.234 g, 1.26 mmol) were added at ambient temperature to a stirred solution of (E)-3-iodo- acrylic acid methyl ester (2.60 g, 12.26 mmol) in triethylamine (40 mL). The mixture was stirred at ambient temperature for 20 hours, diluted with saturated ammonium chloride solution and extracted with ethyl acetate. The combined organic layers were filtered through a short pad of celite, and the filtrate was dried over sodium sulfate and concentrated under reduced pressure. The crude material was purified by column chromatography to give the title compound as a light yellow oil (1.73 g, 85%). 1H-NMR (CDCl3.) delta: 1.26 (s, 9H), 3.74 (s, 3H), 6.13 (d, IH, J = 15.9Hz), 6.76 (d, IH, J = 15.9Hz).
According to the analysis of related databases, 6213-88-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; AUSPEX PHARMACEUTICALS, INC.; WO2008/73863; (2008); A2;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com