Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 135050-44-1, name is 3-Chloro-4-iodoaniline, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 3-Chloro-4-iodoaniline
Diethyl 2-((3-chloro-4-iodophenylamino)methylene)malonate 3-Chloro-4-iodoaniline (3.0 g, 11.8 mmol) and diethyl 2- (ethoxymethylene)malonate (12.78 g, 59.2 mmol) were mixed in a 100 mL single neck flask, and the resulting mixture was heated to 120oC and stirred for 2.5 h. The mixture was allowed to cool to RT and purified by flash column chromatography on silica gel (10-20% ethyl acetate / petroleum ether) to afford the desired product (3.93 g) as a white solid. ESI-MS m/z : 422.1 [M – H]-.
According to the analysis of related databases, 135050-44-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ARAXES PHARMA LLC; LI, Liansheng; FENG, Jun; WU, Tao; REN, Pingda; LIU, Yi; LIU, Yuan; LONG, Yun, Oliver; WO2015/54572; (2015); A1;,
Iodide – Wikipedia,
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