A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 60166-93-0, Name is Iopamidol, molecular formula is C17H22I3N3O8. In an article, author is Vobecky, M,once mentioned of 60166-93-0, Product Details of 60166-93-0.
Uptake of iodide by rat tissues is influenced by an excessive intake of bromide
The effect of an enhanced bromide intake on the uptake of iodide by tissues of rats was studied. It was found that a high level of bromide in these animals caused a marked decrease in iodide concentration in the thyroid, stomach and skin. In other organs (kidneys, liver), no decrease in iodide concentration was observed. In animals maintained under the conditions of iodine deficiency the decrease was inexpressive obviously due to the fact that iodide concentration in all their tissues was already reduced. The results indicate that the effect of an excessive bromide can manifest itself only in organs/tissues which are able to accumulate iodide. The decrease in iodide concentration is probably caused both by the competitive inhibition of an uptake of iodide by superfluous bromide, and by the rise in the renal excretion of iodide due to the excess of bromide in the organism. High uptake of iodide by skin can significantly diminish the losses of absorbed iodide since skin accounts for about 20 % of the rat body weight.
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