Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 619-58-9, Name is 4-Iodobenzoic acid, molecular formula is , belongs to iodides-buliding-blocks compound. In a document, author is Gervay, J, Name: 4-Iodobenzoic acid.
Mechanistic studies on the stereoselective formation of glycosyl iodides: First characterization of beta-D-glycosyl iodides
Treatment of glycosyl acetates with one equivalent of iodotrimethylsilane at low temperature results in the quantitative formation of glycosyl iodides. Carbohydrates that possess a participating group at the C-2 position initially form beta-D-glycosyl iodides, which quickly equilibrate to the alpha-iodo anomers. The beta anomer of peracetylated glucose reacts faster than the alpha anomer, presumably because the C-2 acetate can assist in displacing the silylated anomeric acetate. In contrast, the alpha anomer reacts faster than the beta anomer in substrates lacking a participating group at C-2. For example, activation of 1-O-acetyl-2,3,4,6-tetra-O-benzyl-alpha-D-glucopyranose leads to formation of the beta iodide, while the corresponding beta acetate produces the alpha iodide. Although the beta iodides quickly equilibrate to the alpha anomers, they can be prepared in sizable quantities at low temperatures where equilibration is slow. This report describes the first stereoselective formation and characterization of P-D-glycosyl iodides. (C) 1997 Elsevier Science Ltd.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 619-58-9, in my other articles. Name: 4-Iodobenzoic acid.