Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 105202-02-6, name is 2-Iodo-5-(trifluoromethyl)aniline, This compound has unique chemical properties. The synthetic route is as follows., Formula: C7H5F3IN
In a air atmosphere, 1.0 mmol of 5-carboxymethyl-2-hydroxybenzylalcohol , 1.2 mmol of 5-trifluoromethyl-2-iodoaniline,0.02 mmol p-cymene ruthenium dichloride dimer,0.03 mmol of cuprous iodide, 0.08 mmol of 1,1′-bis (diphenylphosphino) ferrocene,5.0 mmol of sodium hydroxide, and 5 ml of toluene, and then placed on a condenser tube heated to 120 C. with an oil bath with magnetic stirring for 40 hours. The oil bath was removed, 3 ml of water was added to the reaction mixture and the mixture was extracted three times with 5 ml of ethyl acetate. The organic phases were combined and dried over anhydrous magnesium sulfate for 30 minutes. The filtrate was concentrated on a rotary evaporator. The concentrated solid was extracted with methylene chloride , Recrystallized to give pure product 23, yield 81%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 105202-02-6.
Reference:
Patent; Luoyang Normal College; Xu Chen; Li Hongmei; Wang Zhiqiang; Lou Xinhua; Fu Weijun; (11 pag.)CN105949143; (2016); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com