Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 116632-39-4, name is 5-Bromo-2-iodotoluene, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C7H6BrI
4-bromo-1-iodo-2-methylbenzene (31.2 g, 105 mmol), (2-(methoxycarbonyl)phenyl)boronic acid (24.5 g, 136 mmol), Pd(dppf)Cl2 (2.3 g, 3.15 mmol) and potassium carbonate (72.5 g, 525 mmol) were added to 350 mL of toluene in a 1 L three-neck round bottom flask. The resulting mixture was purged with nitrogen for 5 min and refluxed overnight under nitrogen. After cooling to room temperature, the reaction mixture was filtered through Celite and washed with ethyl acetate. The organic extract was dried over anhydrous Na2SO4 and concentrated. The residue was purified by flash column chromatography (eluent: ethyl acetate/petroleum ether=1/100, v/v) to give methyl 4′-bromo-2′-methyl-[1,1′-biphenyl]-2-carboxylate as a light yellow oil (20 g, 62%).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 116632-39-4.
Reference:
Patent; Xia, Chuanjun; (88 pag.)US2019/127406; (2019); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com