Reference of 612-55-5, These common heterocyclic compound, 612-55-5, name is 2-Iodonaphthalene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of aryl halide (1.0 mmol), arylboronic acid (1.2 mmol), K2CO3 (2.0 mmol), DMF-H2O (3-3 ml), and n-dodecane (15-20 mg) as an internal GC standard and 0.5 mol% of catalyst was stirred at 80? C in air. Progress of the reaction was monitored by withdrawing the reaction mixtures periodically and analyzed by GC/GC-MS. GC yields were based on the amount of aryl halide employed. At the end of the reaction, the catalyst was separated by simple filtration. Filtrate was dried over Na2SO4, filtered, concentrated and the residue was purified by flash column chromatography on silica gel. The product was analyzed by GC-MS. All the prepared compounds are known and compared with authentic samples.
Statistics shows that 2-Iodonaphthalene is playing an increasingly important role. we look forward to future research findings about 612-55-5.
Reference:
Article; Islam, Sk. Manirul; Salam, Noor; Mondal, Paramita; Roy, Anupam Singha; Journal of Molecular Catalysis A: Chemical; vol. 366; (2013); p. 321 – 332;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com