In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 58313-23-8 as follows. Recommanded Product: 58313-23-8
B. 3-iodobenzohydrazideIn a schlenck tube, a mixture of ethyl 3-iodobenzoate (1.8Og, 6.52mmol) and hidrazine hydrate (3.18ml, 65.2mmol) in ethanol (25ml) was heated at 8O0C overnight. The solvent was evaporated and the crude redissolved in DCM and washed with water and brine. The organic layer was dried, filtered and concentrated under vacuum to give the title compound as a white solid (88% yield).ESI/MS (m/e, %): 263 [(M+1)+, 100]
According to the analysis of related databases, 58313-23-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; LABORATORIOS ALMIRALL, S.A.; WO2009/21696; (2009); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com