Synthetic Route of 181765-86-6, The chemical industry reduces the impact on the environment during synthesis 181765-86-6, name is Methyl 5-bromo-2-iodobenzoate, I believe this compound will play a more active role in future production and life.
Methyl 5-bromo-2-iodo-benzoate (methyl 5-bromo-2-iodobenzoate) (3.849 g, 11.259 mmol) and compound 23-5 (phenanthren-1-ylboronic acid) (3 g, 13.510 mmol), 2 mol / L potassium carbonate (potassium carbonate) (inH2O, 30 mL), tetrakis (triphenylphosphine) palladium (tetrakis (triphenylphosphine) palladium) (0.651 g, 0.563mmol) in tetrahydrofuran (tetrahydrofuran) and 100 mL of methanol (methanol) 30 mL and mixed under a nitrogen atmosphere it was heated for 24 hours ,after that remove the solvent after confirmation, and the reaction was terminated via TLC celite (celite)Filtered in the following, by using dichloromethane and H2O, the organic layer was separated and washed with, saturated sodium chloride solution and bovineBy filtration using a rhodium sulfate (Sodium sulfate) to remove the moisture. The solvent from the results obtained therefrom(3.5g, 79%)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 5-bromo-2-iodobenzoate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Samsung Display Co. ltd., Samsung Display Co. ltd.; Seoul National University Industrial-Academic Cooperation Foundation; Kim, Se Hoon; Jung, Seong Jin; Hong, Chong In; Kim, Mi Yeong; Choo, Chang Woong; (72 pag.)KR2016/9768; (2016); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com