Reference of 645-00-1, The chemical industry reduces the impact on the environment during synthesis 645-00-1, name is 1-Iodo-3-nitrobenzene, I believe this compound will play a more active role in future production and life.
General procedure: In a typical reaction, a mixture of aryl halides (1.0 mmol), phenylacetylene (1.5 mmol), piperidine (2.0 mmol), H2O (6 ml) and catalyst (0.5 mol% of Pd) was stirred at 100 C for appropriate time. Progress of the reaction was monitored by GC analysis at different time interval of the reaction. After the completion of the reaction, the mixture was cooled to room temperature, diluted with water, and extracted with CH2Cl2 for three times. The organic phase thuscollected was dried with Na2SO4 and concentrated. The crude product was purified by flash column chromatography on silica gel. The product was analyzed by GC/MS, 1H NMR and elemental analyses. All the products were known compounds and were identified by comparison of their physical and spectra data with those of authentic samples.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Iodo-3-nitrobenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Short Survey; He, Ying; Cai, Chun; Journal of Organometallic Chemistry; vol. 696; 13; (2011); p. 2689 – 2692;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com