Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 181765-86-6, name is Methyl 5-bromo-2-iodobenzoate, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of Methyl 5-bromo-2-iodobenzoate
500ml three-necked round bottom flask was charged with methyl 5-bromo-2-iodo benzoate (130g, 0.381mol), as 9-phenanthrene boronic acid(84.7g, 0.381mol), 2% of tetrakis triphenylphosphine palladium (8.82g, 0.008mol), 2M potassium carbonate (100ml), tetrahydrofuran (200ml) was added. 16 hours with stirring and reflux under reduced pressure and then extracted with ethyl acetate concentrate was purified by silica gel column (ethyl acetate: heptane = 1: 5) to give the [intermediate 1-a] (120g, yield = 80.4%).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 181765-86-6.
Reference:
Patent; SFC CO., LTD.; JU MAN, SONG; HEE DAE, KIM; YUR IM, LEE; SANG WOO, PARK; PARK, SEOK BAE, PARK; KYUNG SEOK, JEONG; SOON WOOK, CHA; (36 pag.)KR2015/113642; (2015); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com