Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3718-88-5, name is 3-Iodobenzylamine hydrochloride, This compound has unique chemical properties. The synthetic route is as follows., name: 3-Iodobenzylamine hydrochloride
Example 1 Preparation of N6 -(3-Iodobenzyl)-9-Methyladenine (3) A mixture of 6-chloropurine (1, 100 mg, 0.65 mmol), 3-iodobenzylamine hydrochloride (192 mg, 0.71 mmol), and triethylamine (0.27 mL, 1.94 mmol) in absolute ethanol (2 mL) was heated for 24 h at 80 C. After cooling, the resulting solid was filtered under suction, washed with ethyl acetate, and dried to give compound 2 (191.3 mg, 84.0%). 1 H NMR (DMSO-d6) delta 4.67 (br s, 2 H, CH2), 7.11 (pseudo t, J=7.6 and 7.5 Hz, 1 H, H-16), 7.37 (d, J=7.9 Hz, 1 H, H-17), 7.58 (d, J=7.6 Hz, 1 H, H-15), 7.73 (s, 1 H, H-13), 8.12 and 8.17 (each: s, 1 H, H-8 and H-2), 8.25 (br s, 1 H, exchangeable with D2 O, NH), 12.95 (br s, 1 H, exchangeable with D2 O, N9 H).
According to the analysis of related databases, 3718-88-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; The United States of America as represented by the Department of Health and Human Services; US5688774; (1997); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com